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68179d65be22ee500d53ff54 Card 2

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ANTI HIV MEDICINE

Telura Tablet: The Triple-Combination Breakthrough in HIV-1 Management – Global Supply by Ernest Oncology In the ongoing global effort to manage HIV effectively, Telura stands as a cornerstone of modern Antiretroviral Therapy (ART). As a fixed-dose combination of Tenofovir Disoproxil Fumarate ($300text{mg}$), Lamivudine ($300text{mg}$), and Efavirenz ($600text{mg}$), it simplifies complex treatment schedules into a single, high-efficacy daily pill. What is Telura? Telura is a complete, once-daily regimen for the treatment of HIV-1 infection in adults and pediatric patients weighing at least $40text{kg}$. It is widely recognized for its clinical reliability and is often used as a first-line treatment in various international health protocols. Primary Indications & Medical Uses HIV-1 Infection Treatment: Used to reduce the viral load to undetectable levels, thereby strengthening the immune system. Long-term Maintenance: Provides a stable, long-term solution for patients who are stable on this specific ART combination. Prevention of Transmission: By suppressing the virus, it significantly reduces the risk of transmitting HIV to others (U=U principle). Detailed Product Information: Telura (TDF/3TC/EFV) Feature,Technical Specification Active Ingredients,Tenofovir Disoproxil Fumarate (300mg) + Lamivudine (300mg) + Efavirenz (600mg) Drug Class,NRTI + NtRTI + NNRTI Combination Manufacturer,Mylan (A Viatris Company) / Hetero Labs (India) Form,Film-coated tablets (30 tablets per bottle) Mechanism,Triple-action viral replication inhibition Telura Tablet: The Triple-Combination Breakthrough in HIV-1 Management – Global Supply by Ernest Oncology In the ongoing global effort to manage HIV effectively, Telura stands as a cornerstone of modern Antiretroviral Therapy (ART). As a fixed-dose combination of Tenofovir Disoproxil Fumarate (300mg), Lamivudine (300mg), and Efavirenz (600mg), it simplifies complex treatment schedules into a single, high-efficacy daily pill. Ernest Oncology, the specialized pharmaceutical division of Ernest Pharmaceutical Pvt. Ltd., is a trusted Exporter, Bulk Supplier, and Distributor from India. We facilitate the secure international distribution of Telura to the UK (London), USA, Abu Dhabi (UAE), Australia, and South Africa via specialized pharmaceutical export channels. What is Telura? Telura is a complete, once-daily regimen for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 40kg. It is widely recognized for its clinical reliability and is often used as a first-line treatment in various international health protocols. Primary Indications & Medical Uses HIV-1 Infection Treatment: Used to reduce the viral load to undetectable levels, thereby strengthening the immune system. Long-term Maintenance: Provides a stable, long-term solution for patients who are stable on this specific ART combination. Prevention of Transmission: By suppressing the virus, it significantly reduces the risk of transmitting HIV to others (U=U principle). Detailed Product Information: Telura (TDF/3TC/EFV) Feature Technical Specification Active Ingredients Tenofovir Disoproxil Fumarate (300mg) + Lamivudine (300mg) + Efavirenz (600mg) Drug Class NRTI + NtRTI + NNRTI Combination Manufacturer Mylan (A Viatris Company) / Hetero Labs (India) Form Film-coated tablets (30 tablets per bottle) Mechanism Triple-action viral replication inhibition Mechanism of Action: How it Works Telura attacks the virus using two distinct classes of antiretrovirals: Tenofovir (300mg) & Lamivudine (300mg): These are Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs). They block the reverse transcriptase enzyme, preventing the virus from converting its RNA into DNA. Efavirenz (600mg): A Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) that binds directly to the enzyme to stop it from working. Dosage and Administration Standard Dose: One tablet taken once daily. Administration: It is highly recommended to take Telura on an empty stomach, preferably at bedtime. This helps reduce the severity of potential side effects associated with Efavirenz, such as dizziness or vivid dreams. Consistency: To ensure maximum effectiveness, the tablet should be taken at the same time every day to maintain a steady concentration in the bloodstream. 📞 Contact Ernest Oncology — Pharmaceutical Exporter from India (Group of Ernest Pharmaceutical Pvt. Ltd.) Partner with a verified leader in international antiviral and oncology medicine supply. 🌐 Websites: www.oncologymedicinesupplier.com | www.ernestpharmaceuticals.com | www.ernestimpex.com 📧 Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 🔗 Instant Chat: https://wa.me/919359902383

68179d65be22ee500d53ff54 Card 2

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ANTI HIV MEDICINE

Viropil Tablet: The Advanced Triple-Action HIV Treatment – Global Supply by Ernest Oncology In the modern era of antiretroviral therapy (ART), Viropil represents the pinnacle of “Test and Treat“ efficiency. As a fixed-dose combination of Dolutegravir ($50text{mg}$), Tenofovir Alafenamide ($25text{mg}$), and Lamivudine ($300text{mg}$), it provides a complete, high-barrier regimen in a single daily pill. Ernest Oncology, the specialized pharmaceutical division of Ernest Pharmaceutical Pvt. Ltd., is a trusted Exporter, Bulk Supplier, and Distributor from India. We facilitate the secure international distribution of Viropil to the UK (London), USA, Abu Dhabi (UAE), Australia, and South Africa via specialized pharmaceutical export channels. What is Viropil? Viropil is a generic version of the breakthrough medication Spegra. It is a complete HIV-1 regimen for adults and pediatric patients weighing at least $40text{kg}$. By combining three different classes of antivirals, Viropil suppresses the viral load to undetectable levels, protecting the immune system and preventing transmission. Primary Indications & Medical Uses HIV-1 Infection Treatment: Used as a first-line, single-tablet regimen for newly diagnosed patients and those switching from less effective therapies. High Viral Load Suppression: Highly effective at bringing viral counts down rapidly due to the inclusion of Dolutegravir. Resistance Management: Known for its high genetic barrier to resistance, making it suitable for long-term clinical success. Detailed Product Information: Viropil (DTG/TAF/3TC) Feature,Technical Specification Active Ingredients,Dolutegravir (50mg) + Tenofovir Alafenamide (25mg) + Lamivudine (300mg) Drug Class,INSTI + NRTI + NtRTI Combination Manufacturer,Emcure Pharmaceuticals (India) Form,Film-coated tablets (30 tablets per bottle) Benefits of TAF,Lower bone and kidney toxicity compared to older Tenofovir (TDF) Mechanism of Action: Triple-Layer Protection Viropil works by attacking the virus at different stages of its life cycle: Dolutegravir: An Integrase Strand Transfer Inhibitor (INSTI) that prevents the viral DNA from integrating into the human cell's DNA. Tenofovir Alafenamide & Lamivudine: Both are Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs) that stop the virus from creating new copies of itself. Dosage and Administration Standard Dose: One tablet taken once daily. Administration: Can be taken with or without food. It is crucial to maintain a consistent schedule to prevent viral rebound. Safety Profile: Viropil is generally well-tolerated, with fewer renal and bone-density side effects due to the advanced Tenofovir Alafenamide (TAF) component. Global Reach: Exporting to UK, USA, UAE, Australia, and South Africa Ernest Oncology excels in the logistics of critical antiretrovirals. We ensure that Viropil—manufactured in world-class facilities—reaches international healthcare providers and patients through verified legal pathways. United Kingdom & London: Supporting private health clinics and specialized HIV care networks throughout the UK. United States: Providing affordable access for research and specialized pharmacy requirements. Abu Dhabi & UAE: Rapid export to the Middle East's leading specialty medicine hubs. Australia & South Africa: Reliable bulk supply for public health initiatives and regional distributors. 📞 Contact Ernest Oncology — Pharmaceutical Exporter from India (Group of Ernest Pharmaceutical Pvt. Ltd.) Partner with a verified leader in international antiviral and oncology medicine supply. 🌐 Websites: www.oncologymedicinesupplier.com | www.ernestpharmaceuticals.com | www.ernestimpex.com | www.ernestvision.com 📧 Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 🔗 Instant Chat: https://wa.me/919359902383

68179d65be22ee500d53ff54 Card 2

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ANTI HIV MEDICINE

Velpanat Tablet (Sofosbuvir 400mg & Velpatasvir 100mg): The Pan-Genotypic Cure for Hepatitis C – Global Supply by Ernest Oncology In the field of hepatology and antiviral research, Velpanat represents a historic milestone. As a fixed-dose combination of Sofosbuvir and Velpatasvir, it is the first “pan-genotypic“ treatment—meaning it is highly effective against all six major genotypes (1-6) of the Hepatitis C Virus (HCV). Ernest Oncology, a specialized division of Ernest Pharmaceutical Pvt. Ltd., is a trusted Exporter, Bulk Supplier, and Distributor from India. We facilitate the secure international distribution of Velpanat to the UK (London), USA, Abu Dhabi (UAE), Australia, and South Africa via specialized pharmaceutical export channels. What is Velpanat? Velpanat is a generic version of the breakthrough medication Epclusa. It combines two powerful direct-acting antivirals (DAAs) into a single, once-daily tablet. By targeting the virus directly, Velpanat can achieve cure rates exceeding 95% in most patient populations. Primary Indications & Medical Uses Chronic Hepatitis C (Genotypes 1-6): Used to treat adults and children (aged 3 years and older) with chronic HCV infection. Patients with Cirrhosis: Effective for patients without cirrhosis or those with compensated cirrhosis. Decompensated Cirrhosis: When used in combination with Ribavirin, it is a primary choice for patients with advanced (decompensated) liver scarring. Feature,Technical Specification Active Ingredients,Sofosbuvir (400mg) + Velpatasvir (100mg) Drug Class,Direct-Acting Antivirals (DAAs) Mechanism,NS5B Polymerase Inhibitor + NS5A Inhibitor Manufacturer,Natco Pharma Ltd. (India) Form,Film-coated tablets (28 tablets per bottle) Success Rate,Over 95% Sustained Virologic Response (SVR) Velpanat Tablet (Sofosbuvir 400mg & Velpatasvir 100mg): The Pan-Genotypic Cure for Hepatitis C – Global Supply by Ernest Oncology In the field of hepatology and antiviral research, Velpanat represents a historic milestone. As a fixed-dose combination of Sofosbuvir and Velpatasvir, it is the first “pan-genotypic“ treatment—meaning it is highly effective against all six major genotypes (1-6) of the Hepatitis C Virus (HCV). Ernest Oncology, a specialized division of Ernest Pharmaceutical Pvt. Ltd., is a trusted Exporter, Bulk Supplier, and Distributor from India. We facilitate the secure international distribution of Velpanat to the UK (London), USA, Abu Dhabi (UAE), Australia, and South Africa via specialized pharmaceutical export channels. What is Velpanat? Velpanat is a generic version of the breakthrough medication Epclusa. It combines two powerful direct-acting antivirals (DAAs) into a single, once-daily tablet. By targeting the virus directly, Velpanat can achieve cure rates exceeding 95% in most patient populations. Primary Indications & Medical Uses Chronic Hepatitis C (Genotypes 1-6): Used to treat adults and children (aged 3 years and older) with chronic HCV infection. Patients with Cirrhosis: Effective for patients without cirrhosis or those with compensated cirrhosis. Decompensated Cirrhosis: When used in combination with Ribavirin, it is a primary choice for patients with advanced (decompensated) liver scarring. Detailed Product Information: Velpanat 400mg/100mg Feature Technical Specification Active Ingredients Sofosbuvir (400mg) + Velpatasvir (100mg) Drug Class Direct-Acting Antivirals (DAAs) Mechanism NS5B Polymerase Inhibitor + NS5A Inhibitor Manufacturer Natco Pharma Ltd. (India) Form Film-coated tablets (28 tablets per bottle) Success Rate Over 95% Sustained Virologic Response (SVR) Mechanism of Action: How It Works Velpanat uses a “double-lock“ mechanism to eradicate the virus: Sofosbuvir (400mg): Acts as a “chain terminator.“ It mimics the virus's genetic building blocks, tricking the NS5B polymerase enzyme into stopping the replication of viral RNA. Velpatasvir (100mg): Targets the NS5A protein, which is essential for both the replication and the assembly of new virus particles. Dosage and Administration Standard Dose: One tablet taken once daily for a duration of 12 weeks. Administration: Can be taken with or without food. It is vital to take the tablet at the same time every day to maintain consistent medicine levels in the blood. Full Course: Patients must complete the entire 12-week course even if they begin to feel better within the first few days. 📞 Contact Ernest Oncology — Pharmaceutical Exporter from India (Group of Ernest Pharmaceutical Pvt. Ltd.) Partner with a verified leader in international antiviral and oncology medicine supply. 🌐 Websites: www.oncologymedicinesupplier.com | www.ernestpharmaceuticals.com | www.ernestimpex.com 📧 Email: exports@ernestpharmaceuticals.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 93599 02383 🔗 Instant Chat: https://wa.me/919359902383

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