Global Exporter & Bulk Supplier of Oxalieva 100 mg Injection

🌍 Introduction

Are you looking for a trusted and globally compliant exporter of Oxalieva 100 mg Injection? At Ernest Oncology (a division of Ernest Pharmaceutical Pvt. Ltd.), we specialize in the secure, compliant, and efficient supply chain management and distribution of critical oncology formulations, including Oxaliplatin 100 mg injections, to hospitals, pharmacies, and pharmaceutical distributors worldwide.

🔬 1. Product Overview: Oxalieva 100 mg Injection

Oxalieva 100 mg Injection contains Oxaliplatin, a third-generation, platinum-based antineoplastic agent widely used in combination therapies to treat various solid tumors.

• Composition: Oxaliplatin USP 100 mg

• Therapeutic Class: Platinum coordination complex / Antineoplastic agent

• Formulation Type: Sterile solution for intravenous (IV) infusion

• Storage Temperature: Store below 25°C. Protect from light. Do not freeze.

⚙️ 2. Mechanism of Action

Oxalieva functions as an alkylating-like agent that interferes with the genetic material of cancer cells:

• DNA Cross-linking: The compound penetrates the cell membrane, aquates, and binds to DNA strands to form inter-strand and intra-strand cross-links.

• Inhibition of Synthesis: This binding interrupts the spatial structure of DNA, blocking both replication and transcription processes.

• Apoptosis: The unrepairable genetic damage triggers programmed cell death (apoptosis) in rapidly dividing malignant cells.

🏥 3. Therapeutic Indications

Oxalieva 100 mg Injection is indicated for:

• Colorectal Cancer: Adjuvant treatment of stage III colon cancer after complete resection of the primary tumor.

• Metastatic Colorectal Cancer: First- and second-line treatment of advanced colorectal cancer, usually combined with 5-fluorouracil and leucovorin.

⚠️ 4. Administration & Safety Guidelines

• Route of Administration: Administered exclusively via Intravenous (IV) infusion. It is diluted in a 5% Dextrose solution and administered slowly under clinical supervision.

• Compatibility Warning: Do not use needles or administration sets containing aluminum components, as a chemical reaction will cause precipitation and loss of potency.

• Side Effects & Precautions: Common side effects include nausea, vomiting, fatigue, loss of appetite, and peripheral sensory neuropathy. Serious risks include bone marrow suppression, ototoxicity, and severe allergic reactions.

📞 Contact Ernest Oncology — Medicine Exporter

(GROUP OF ERNEST PHARMACEUTICAL PVT. LTD.)